Description

1-(Bromomethyl)-4-(Trifluoromethyl)Cyclohexane is a versatile and high-value organobromine building block characterized by its reactive bromomethyl group and stable trifluoromethyl substituent. This compound is essential for introducing both bromoalkyl and fluorinated moieties into complex molecular architectures, enabling the synthesis of advanced materials and pharmaceuticals. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of compounds with enhanced metabolic stability and bioavailability via the trifluoromethyl group.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the cyclohexane scaffold and fluorine atoms contribute to product efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties like hydrophobicity, chemical resistance, and thermal stability.
• Cross-coupling Reactions: The bromomethyl moiety acts as an effective handle for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial research focused on exploring the unique effects of fluorine in organic molecules.

Basic Information

Product Name	1-(Bromomethyl)-4-(Trifluoromethyl)Cyclohexane
CAS No.	858121-96-7
Molecular Formula	C8H12BrF3
Molecular Weight	245.08 g/mol
Synonyms	4-(Trifluoromethyl)cyclohexylmethyl bromide; (4-(Trifluoromethyl)cyclohexyl)methyl bromide; 1-Bromomethyl-4-trifluoromethylcyclohexane; α-Bromo-4-(trifluoromethyl)cyclohexanemethane; Bromomethyl(4-trifluoromethylcyclohexane)
EINECS	Contact for details

Quality Control

Every batch of 1-(Bromomethyl)-4-(Trifluoromethyl)Cyclohexane is produced and analyzed under strict quality management protocols. We guarantee high-purity material suitable for demanding synthetic applications. Our standard quality assurance includes rigorous testing for identity, purity, and impurity profiles using advanced analytical techniques. Certificates of Analysis (COA) documenting full specifications are provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.