Description

(2E)-3-(2,6-Difluoro-4-Methoxyphenyl)-2-Propenoic Acid Ethyl Ester is a high-purity, synthetic organic intermediate characterized by its difluorinated aromatic structure and α,β-unsaturated ester moiety. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the introduction of a specific fluorinated pharmacophore. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzyme pathways where the difluoromethoxyphenyl group is critical.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its unique fluorinated aromatic system.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Ligand and Catalyst Development: Employed in the preparation of complex organic ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological processes.

Basic Information

Product Name	(2E)-3-(2,6-Difluoro-4-Methoxyphenyl)-2-Propenoic Acid Ethyl Ester
CAS No.	858114-78-0
Molecular Formula	C₁₂H₁₂F₂O₃
Molecular Weight	242.22 g/mol
Synonyms	Ethyl (2E)-3-(2,6-Difluoro-4-methoxyphenyl)acrylate; Ethyl (E)-3-(2,6-Difluoro-4-methoxyphenyl)propenoate; 2,6-Difluoro-4-methoxycinnamic Acid Ethyl Ester; (E)-Ethyl 3-(2,6-Difluoro-4-methoxyphenyl)acrylate; 858114-78-0; Ethyl 3-(2,6-Difluoro-4-methoxyphenyl)-2-propenoate
EINECS	Contact for details

Quality Control

Every batch of (2E)-3-(2,6-Difluoro-4-Methoxyphenyl)-2-Propenoic Acid Ethyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles verified by HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.