Description

L-Valine, 3-Methyl-n-[2-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]-, 1,1-Dimethylethyl Ester is a protected amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the construction of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of custom peptides for drug discovery and development.
• Peptidomimetic Research: Used to create modified peptide structures with enhanced stability, bioavailability, or specific biological activity.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or labels in diagnostic assay development.
• Academic & R&D Laboratories: Employed in fundamental research exploring protein-protein interactions, enzyme mechanisms, and structural biology.
• Chemical Biology Probes: Integral for synthesizing activity-based probes and other tools used to study biological processes at the molecular level.

Basic Information

Product Name	L-Valine, 3-Methyl-n-[2-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	858034-68-1
Molecular Formula	C20H30N2O5
Molecular Weight	378.47 g/mol
Synonyms	Boc-Valine(Z-Lys-OH)-OtBu; N2-[(Benzyloxy)carbonyl]-N6-(tert-butoxycarbonyl)-L-lysyl-L-valine tert-butyl ester; (2S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-6-[[(phenylmethoxy)carbonyl]amino]hexanoic acid tert-butyl ester; Z-Lys(Boc)-Val-OtBu; Fmoc-Lys(Z)-Val-OtBu precursor; Protected L-Valyl-L-lysine derivative; tert-Butyl N-[(benzyloxy)carbonyl]-N-[2-[[(2S)-2-[(2-methylpropanoyl)amino]-3-methylbutanoyl]amino]ethyl]carbamate
EINECS	Contact for details

Quality Control

Every batch of our L-Valine derivative is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, essential for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.