Description

o-(2-Aminoethyl)-o-(2-Azidoethyl)Heptaethylene Glycol is a heterobifunctional polyethylene glycol (PEG) derivative engineered for advanced bioconjugation and materials science applications. This compound is critical for researchers and manufacturers requiring precise, site-specific crosslinking due to its orthogonal amine and azido reactive groups. It is primarily utilized in the development of PEGylated therapeutics, diagnostic probes, hydrogels, and surface functionalization across the pharmaceutical and biotechnology sectors.

Application

• Bioconjugation Linker: For site-specific coupling of biomolecules (e.g., proteins, peptides, antibodies) via amine-reactive and azide-alkyne click chemistry pathways.
• PEGylation Reagent: Used to modify therapeutic proteins and peptides to enhance solubility, stability, and circulation half-life.
• Hydrogel Formation: Serves as a crosslinking agent in the synthesis of biocompatible hydrogels for drug delivery and tissue engineering.
• Surface Modification: Functionalizes nanoparticles, quantum dots, and biosensor surfaces to create bio-inert or bioactive coatings.
• Diagnostic Probe Synthesis: Facilitates the construction of advanced imaging and diagnostic agents by linking targeting moieties to reporter molecules.
• ADC (Antibody-Drug Conjugate) Development: Enables the controlled attachment of cytotoxic payloads to antibodies.
• Polymer Chemistry: Acts as a versatile monomer or macromonomer for synthesizing functionalized, water-soluble polymers.

Basic Information

Product Name	o-(2-Aminoethyl)-o-(2-Azidoethyl)Heptaethylene Glycol
CAS No.	857891-82-8
Molecular Formula	C22H46N4O8
Molecular Weight	494.63 g/mol
Synonyms	8-Aza-3,6,9,12,15,18,21-heptaoxatetratriacont-33-yn-1-amine; Amino-PEG7-Azide; α-Amino-ω-azido-heptaethylene glycol; N-(2-Aminoethyl)-N'-(2-azidoethyl)heptaethylene glycol; Heterobifunctional PEG Amine Azide; Amine-PEG7-N3; Azido-PEG7-Amine; 2,5,8,11,14,17,20-Heptaoxadocosan-22-yn-1-amine
EINECS	Contact for details

Quality Control

Our o-(2-Aminoethyl)-o-(2-Azidoethyl)Heptaethylene Glycol is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive research and GMP applications. Each lot is characterized by NMR, HPLC, and mass spectrometry to confirm structure, purity, and functional group integrity. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and/or storage under an inert atmosphere to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details
Azide Content (IR/NMR)	Contact for details
Molecular Weight (MS)	494.63 ± 5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.