Description

(4S,5R)-(-)-4-Benzyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl)-2-Oxazolidinone, 99% is a high-purity, chiral oxazolidinone auxiliary featuring a unique perfluorinated side chain. This compound is a critical building block in asymmetric synthesis, valued for its ability to direct stereoselectivity in complex organic transformations, particularly for the introduction of fluorinated motifs. It is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who require precise control over molecular architecture. The product is supplied at a guaranteed purity of 99% to ensure consistent and reliable performance in demanding synthetic applications.

Application

• Asymmetric Synthesis Auxiliary: As a chiral Evans-type auxiliary for the stereocontrolled alkylation, aldol, and Diels-Alder reactions, enabling the synthesis of enantiomerically pure intermediates.
• Pharmaceutical Intermediate: For the research and development of novel Active Pharmaceutical Ingredients (APIs), especially those incorporating fluorinated groups to modulate bioavailability and metabolic stability.
• Fluorochemical Research: Serves as a key precursor in the development of specialty fluorinated compounds for materials science, including surfactants and liquid crystals.
• Agrochemical Synthesis: Used in creating advanced, chiral agrochemicals where the fluorinated chain can enhance biological activity and environmental persistence.
• Catalyst and Ligand Development: As a scaffold for developing novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Process R&D: A valuable tool in academic laboratories and industrial R&D for methodology development and scale-up studies.

Basic Information

Product Name	(4S,5R)-(-)-4-Benzyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl)-2-Oxazolidinone, 99%
CAS No.	857637-92-4
Molecular Formula	C24H20F13NO2
Molecular Weight	577.41 g/mol
Synonyms	(4S,5R)-4-Benzyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone; (4S,5R)-4-Benzyl-5-(perfluorooctyl)oxazolidin-2-one; (4S,5R)-(-)-4-Benzyl-5-(1H,1H,2H,2H-perfluorooctyl)-2-oxazolidinone; Evans Auxiliary with perfluorooctyl chain; Chiral fluorinated oxazolidinone; F13-Oxazolidinone auxiliary; (4S,5R)-4-Benzyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (4S,5R)-(-)-4-Benzyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl)-2-Oxazolidinone, 99% is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral HPLC, NMR (1H, 13C, 19F), and mass spectrometry, to confirm identity, enantiomeric purity, and chemical purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.