Description

3-Hydroxy-1-Pyrrolidineacetonitrile is a versatile pyrrolidine-based nitrile compound, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a hydroxyl group and a nitrile moiety, makes it invaluable for constructing complex pharmacophores and fine-tuning molecular properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials where precise molecular architecture is required.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	3-Hydroxy-1-Pyrrolidineacetonitrile
CAS No.	857637-01-5
Molecular Formula	C6H10N2O
Molecular Weight	126.16 g/mol
Synonyms	1-(Cyanomethyl)-3-pyrrolidinol; 3-Hydroxy-1-(cyanomethyl)pyrrolidine; 1-Pyrrolidineacetonitrile, 3-hydroxy-; (3-Hydroxypyrrolidin-1-yl)acetonitrile; 3-Hydroxy-N-(cyanomethyl)pyrrolidine; Pyrrolidine, 1-(cyanomethyl)-3-hydroxy-; 3-Hydroxy-1-pyrrolidineacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-1-Pyrrolidineacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.