Description

3-(Morpholin-4-Ylmethyl)Benzonitrile is a versatile and high-value organic building block featuring a benzonitrile core substituted with a morpholinylmethyl group. This compound is of significant interest for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, kinase inhibition, and other therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the morpholine moiety's bioactivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(Morpholin-4-Ylmethyl)Benzonitrile
CAS No.	857283-91-1
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	3-(Morpholinomethyl)benzonitrile; 3-Morpholin-4-ylmethyl-benzonitrile; 4-[(3-Cyanophenyl)methyl]morpholine; m-(Morpholinomethyl)benzonitrile; Benzonitrile, 3-[(4-morpholinyl)methyl]-; 857283-91-1; 3-Morpholin-4-ylmethylbenzonitrile
EINECS	Contact for details

Quality Control

Our 3-(Morpholin-4-Ylmethyl)Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.