Description

Tetrahydrogestrinone-D4 is a deuterated analog of the synthetic anabolic steroid gestrinone, specifically designed for use as an internal standard in analytical chemistry. This high-purity, isotopically labeled compound is critical for ensuring the accuracy and reliability of mass spectrometry-based analyses, particularly in anti-doping and forensic toxicology. It is an essential reference material for laboratories requiring precise quantification of gestrinone and its metabolites in complex biological matrices.

Application

• Primary use as an Internal Standard (IS) for the quantification of gestrinone in biological samples via LC-MS/MS and GC-MS.
• Critical component in anti-doping control programs for sports agencies and WADA-accredited laboratories.
• Reference material for forensic and clinical toxicology investigations.
• Method development and validation in pharmaceutical research and bioanalytical studies.
• Use in metabolite profiling and pharmacokinetic studies of gestrinone.
• Quality control and assurance for the production of reference standards and calibration kits.

Basic Information

Product Name	Tetrahydrogestrinone-D4
CAS No.	856893-82-8
Molecular Formula	C21H22D4O2
Molecular Weight	314.46 g/mol
Synonyms	13β-Ethyl-17α-ethynyl-17β-hydroxy-18,19,20,21-tetranor-5β,9β,10α-pregna-2,4,6-trien-3-one-d4; 18,19,20,21-Tetranorgestrinone-d4; δ6,7-Dehydrogestrinone-d4; Deuterated Tetrahydrogestrinone; THG-d4; Gestrinone-d4 Internal Standard; Deuterium-labeled THG
EINECS	Contact for details

Quality Control

Every batch of Tetrahydrogestrinone-D4 is manufactured under controlled conditions and undergoes comprehensive analytical characterization to ensure identity, purity, and isotopic enrichment. Our quality assurance protocol includes NMR, HPLC, and mass spectrometry to confirm chemical and isotopic purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data. We adhere to ISO 17034 guidelines for reference material producers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.