Description

(S)-2-Methyl-n-(4-Methylbenzylidene)Propane-2-Sulfinamide CAS NO 856562-52-2 is a high-purity chiral sulfinamide compound, widely recognized as a versatile and critical chiral auxiliary in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, offering researchers and manufacturers precise control over the three-dimensional architecture of target compounds. This intermediate is essential for pharmaceutical R&D, agrochemical synthesis, and advanced material science, where the introduction of specific stereocenters is paramount for biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key chiral auxiliary in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for constructing amines and other nitrogen-containing stereocenters.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and insecticides to enhance efficacy and reduce environmental impact.
• Catalyst and Ligand Precursor: Serves as a building block for the development of novel chiral catalysts and ligands used in transition metal-catalyzed reactions.
• Academic and Industrial Research: A valuable tool for methodological development in organic chemistry for creating libraries of chiral compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(S)-2-Methyl-n-(4-Methylbenzylidene)Propane-2-Sulfinamide
CAS No.	856562-52-2
Molecular Formula	C12H17NOS
Molecular Weight	223.33 g/mol
Synonyms	(S)-N-(4-Methylbenzylidene)-2-methylpropane-2-sulfinamide; (S)-2-Methyl-2-propanesulfinamide, N-[(4-methylphenyl)methylene]-; (S)-p-Tolualdehyde tert-Butanesulfinimine; (S)-N-(p-Tolylidene)-tert-butanesulfinamide; (S)-tert-Butanesulfinamide p-tolualdimine; Ellman's Sulfinamide Derivative; Chiral Sulfinyl Imine; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-n-(4-Methylbenzylidene)Propane-2-Sulfinamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for sensitive asymmetric synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.