Description

8-Oxa-Bicyclo[3.2.1]Octane-3-Carbonitrile is a high-purity, specialized bicyclic nitrile compound used as a critical building block in advanced organic synthesis. This compound matters for its unique oxa-bridged bicyclic structure, which provides a rigid, three-dimensional scaffold valuable for creating novel molecules with specific biological or material properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or antiviral targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, or insecticides, leveraging its constrained bicyclic framework.
• Medicinal Chemistry: Employed as a versatile scaffold for constructing compound libraries in drug discovery programs aimed at probing new biological space.
• Material Science Research: Acts as a precursor or monomer for developing specialty polymers or advanced organic materials with specific optical or electronic properties.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex target molecules.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, including cycloaddition reactions or asymmetric catalysis.

Basic Information

Product Name	8-Oxa-Bicyclo[3.2.1]Octane-3-Carbonitrile
CAS No.	855386-64-0
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	8-Oxabicyclo[3.2.1]octane-3-carbonitrile; 3-Cyano-8-oxabicyclo[3.2.1]octane; 8-Oxa-3-azabicyclo[3.2.1]octane-3-carbonitrile (incorrect but common search variant); Bicyclo[3.2.1]octane-3-carbonitrile, 8-oxa-; Oxabicyclooctanecarbonitrile
EINECS	Contact for details

Quality Control

Our 8-Oxa-Bicyclo[3.2.1]Octane-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.