Description

Benzonitrile, 2-Acetyl-4-Chloro- CAS NO 855291-07-5 is a specialized chlorinated aromatic nitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both acetyl and nitrile functional groups, makes it a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for molecules containing chlorinated aromatic or heterocyclic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the chlorobenzonitrile moiety is a core structural element.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for the preparation of electron-transport or host materials in organic electronic applications.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized colorants and photographic chemicals.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and cyanation reactions.

Basic Information

Product Name	Benzonitrile, 2-Acetyl-4-Chloro-
CAS No.	855291-07-5
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	2-Acetyl-4-chlorobenzonitrile; 4-Chloro-2-acetylbenzonitrile; 1-(4-Chloro-2-cyanophenyl)ethan-1-one; 2-Cyano-5-chloroacetophenone; (4-Chloro-2-cyanophenyl) methyl ketone
EINECS	Contact for details

Quality Control

Our production of 2-Acetyl-4-chlorobenzonitrile adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.