Description

2-Fluoro-3-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorinated phenylboronic acid moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and in the development of new catalytic systems.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tools for studying biological processes, leveraging its boronic acid group for selective binding.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis organizations (CSOs) and CROs serving the global life sciences industry.

Basic Information

Product Name	2-Fluoro-3-Isopropoxyphenylboronic Acid
CAS No.	855230-63-6
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(2-Fluoro-3-isopropoxyphenyl)boronic Acid; 2-Fluoro-3-(1-methylethoxy)benzeneboronic Acid; 3-Isopropoxy-2-fluorophenylboronic Acid; Boronic acid, B-(2-fluoro-3-isopropoxyphenyl)-; 2-Fluoro-3-isopropoxybenzeneboronic acid; 855230-63-6; AKOS005258169
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full batch traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.