Description

2-Fluoro-3-Hydroxyphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the hydroxyl group provides a handle for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex fluorinated aromatic scaffolds found in active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with enhanced activity and environmental profiles.
• Material Science: Precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and sensors that utilize boronic acid-diol interactions.
• Cross-Coupling Reactions: A versatile reagent in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl structures.
• Research & Development: Serves as a standard reagent in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	2-Fluoro-3-Hydroxyphenylboronic Acid
CAS No.	855230-60-3
Molecular Formula	C6H6BFO3
Molecular Weight	155.92 g/mol
Synonyms	(2-Fluoro-3-hydroxyphenyl)boronic acid; 3-Borono-2-fluorophenol; 2-Fluoro-3-hydroxybenzeneboronic acid; 2-Fluoro-3-phenolboronic acid; B-(2-Fluoro-3-hydroxyphenyl)boronic acid; 2-Fluoro-3-dihydroxyborylphenol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccator or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.