Description

4-Fluoro-3-Methoxyphenylboronic Acid is a versatile and high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic semiconductors, where the fluorine and methoxy substituents tune electronic properties.
• Chemical Biology & Probe Development: Utilized to create molecular probes and bioconjugates for studying biological processes and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Fluoro-3-Methoxyphenylboronic Acid
CAS No.	854778-31-7
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(4-Fluoro-3-methoxyphenyl)boronic acid; 3-Methoxy-4-fluorophenylboronic acid; 4-Fluoro-3-methoxybenzeneboronic acid; 4-Fluoro-m-anisylboronic acid; Boronic acid, B-(4-fluoro-3-methoxyphenyl)-; 854778-31-7; 4-Fluoro-3-methoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.