Description

Boc-4-Aminohippuric Acid CAS NO 854621-90-2 is a protected derivative of the amino acid glycine, specifically designed for advanced organic synthesis and peptide research. This compound serves as a crucial building block for the controlled introduction of the hippuric acid moiety, enabling the synthesis of complex molecules with high precision. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers in the development of novel active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to construct specific peptide sequences.
• Bioconjugation: Acts as a linker or spacer molecule for attaching functional groups to biomolecules like proteins or antibodies in bioconjugation chemistry.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides temporary protection for the amine functionality during multi-step synthetic routes.
• Biochemical Research: Employed in the synthesis of substrates, inhibitors, or labeled compounds for enzymatic and metabolic studies.
• Fine Chemical Production: Serves as a specialized intermediate for the custom synthesis of high-value, complex organic molecules.

Basic Information

Product Name	Boc-4-Aminohippuric Acid
CAS No.	854621-90-2
Molecular Formula	C₁₄H₁₈N₂O₅
Molecular Weight	294.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-aminohippuric Acid; N-Boc-4-Aminohippuric Acid; 4-[[(2-{[(tert-Butoxy)carbonyl]amino}acetyl)amino]benzoic Acid; (4-{[(2-{[(tert-Butoxy)carbonyl]amino}acetyl)amino]}benzoic Acid; Boc-Ahx-OH (context-dependent); N-α-Boc-4-Aminohippuric Acid; BOC-AHA
EINECS	Contact for details

Quality Control

Our Boc-4-Aminohippuric Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability and consistency for our customers' critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.