Description

n-(2,4-Difluorophenyl)-n-(4-Formyl-1,3-Thiazol-2-Yl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern medicinal chemistry, ensuring precise molecular construction. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on developing novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in areas requiring complex heterocyclic architectures.
• Agrochemical Synthesis: Serves as a precursor in the development of next-generation fungicides and herbicides, leveraging its difluorophenyl and thiazole motifs.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• API Manufacturing: Employed in the scaled-up synthesis of active pharmaceutical ingredients that incorporate this specific molecular framework.
• Chemical Biology Probes: Utilized in the creation of specialized probes and tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	n-(2,4-Difluorophenyl)-n-(4-Formyl-1,3-Thiazol-2-Yl)Acetamide
CAS No.	854035-88-4
Molecular Formula	C12H7F2N3O2S
Molecular Weight	295.26 g/mol
Synonyms	N-(2,4-Difluorophenyl)-N-(4-formyl-1,3-thiazol-2-yl)acetamide; 2,4-Difluoro-N-(4-formylthiazol-2-yl)-N-phenylacetamide; Acetamide, N-(2,4-difluorophenyl)-N-(4-formyl-2-thiazolyl)-; 854035-88-4; 2-(2,4-Difluorophenyl)(4-formyl-1,3-thiazol-2-yl)amino)-2-oxoethan-1-one (alternative representation)
EINECS	Contact for details

Quality Control

Our n-(2,4-Difluorophenyl)-n-(4-Formyl-1,3-Thiazol-2-Yl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.