Description

2-Chloro-3-Methoxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and methoxy substituents on the benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities. Its utility extends to material science applications where specific aromatic frameworks are required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its substituted aromatic ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers requiring specific electronic properties.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry programs and library synthesis in drug discovery.
• Dye and Pigment Intermediate: Can be used in the synthesis of complex dyes and functional colorants.

Basic Information

Product Name	2-Chloro-3-Methoxybenzonitrile
CAS No.	853331-52-9
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	2-Chloro-3-methoxybenzonitrile; 3-Methoxy-2-chlorobenzonitrile; 2-Chloro-3-methoxybenzene carbonitrile; 2-Chloro-m-anisonitrile; Benzonitrile, 2-chloro-3-methoxy-; (2-Chloro-3-methoxyphenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.