Description

5-Bromo-N-(3-Chlorophenyl)-2-Fluorobenzamide is a high-purity, halogenated benzamide derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides, leveraging its halogen-substituted aromatic structure.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with specific electronic or thermal properties.
• Chemical Biology Probe: Employed in academic and industrial research to study protein-ligand interactions or enzyme mechanisms due to its modifiable benzamide core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-N-(3-Chlorophenyl)-2-Fluorobenzamide
CAS No.	853317-28-9
Molecular Formula	C13H8BrClFNO
Molecular Weight	328.56 g/mol
Synonyms	5-Bromo-N-(3-chlorophenyl)-2-fluorobenzamide; 2-Fluoro-5-bromo-N-(3-chlorophenyl)benzamide; N-(3-Chlorophenyl)-5-bromo-2-fluorobenzamide; Benzamide, 5-bromo-N-(3-chlorophenyl)-2-fluoro-; 853317-28-9; 5-Bromo-2-fluoro-N-(3-chlorophenyl)benzamide
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-N-(3-Chlorophenyl)-2-Fluorobenzamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.