Description

1-Acetyl-2-Pyrrolidinecarboxylic Acid Hydrate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in nitrogen-containing heterocycles. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyrrolidine core structure.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Integral for designing and synthesizing peptide analogs and protease inhibitors in medicinal chemistry.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Specialty Polymer Additive: Acts as a monomer or functional modifier in the production of specialty polymers with tailored properties.

Basic Information

Product Name	1-Acetyl-2-Pyrrolidinecarboxylic Acid Hydrate
CAS No.	852228-03-6
Molecular Formula	C7H11NO3 • xH2O
Molecular Weight	157.17 (Anhydrous basis)
Synonyms	1-Acetylpyrrolidine-2-carboxylic Acid Hydrate; N-Acetyl-DL-proline Hydrate; (RS)-1-Acetyl-2-pyrrolidinecarboxylic Acid Hydrate; 2-Pyrrolidinecarboxylic Acid, 1-acetyl-, Hydrate; N-Acetylproline Hydrate; APCA Hydrate; 1-Acetylproline Hydrate; Acetylproline Hydrate
EINECS	Contact for details

Quality Control

Every batch of 1-Acetyl-2-Pyrrolidinecarboxylic Acid Hydrate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.