Description

[[1-(3-Fluorophenyl)-1H-Imidazol-2-Yl]Thio]Acetic Acid is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique imidazole-thioacetic acid scaffold provides valuable functional handles for further derivatization. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazole and fluorophenyl motifs.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Investigated as a monomer or functional additive for creating novel polymers with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical architecture.

Basic Information

Product Name	[[1-(3-Fluorophenyl)-1H-Imidazol-2-Yl]Thio]Acetic Acid
CAS No.	851879-33-9
Molecular Formula	C11H9FN2O2S
Molecular Weight	252.26 g/mol
Synonyms	2-[[1-(3-Fluorophenyl)-1H-imidazol-2-yl]thio]acetic acid; [[1-(3-Fluorophenyl)-1H-imidazol-2-yl]sulfanyl]acetic acid; 1-(3-Fluorophenyl)-1H-imidazole-2-thiol acetic acid derivative; (1-(3-Fluorophenyl)-1H-imidazol-2-ylthio)acetic acid; 851879-33-9; 3-Fluorophenyl imidazole thioacetic acid
EINECS	Contact for details

Quality Control

Our [[1-(3-Fluorophenyl)-1H-Imidazol-2-Yl]Thio]Acetic Acid is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.