Description

2-Chloro-6-(Trifluoromethyl)Phenylboronic Acid is a high-purity, synthetically valuable organoboron building block essential for modern cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex molecules, particularly in the development of advanced materials and active pharmaceutical ingredients. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for synthesizing novel drug candidates, especially those containing trifluoromethyl and chloro-substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the chlorotrifluoromethylphenyl moiety can impart unique biological activity and stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or monomers for specialty polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and imaging agents for biochemical research and diagnostic applications.
• Catalyst & Ligand Preparation: Useful for the synthesis of novel ligands in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Phenylboronic Acid
CAS No.	851756-52-0
Molecular Formula	C7H5BClF3O2
Molecular Weight	223.38 g/mol
Synonyms	(2-Chloro-6-(trifluoromethyl)phenyl)boronic acid; 2-Chloro-α,α,α-trifluoro-m-tolylboronic acid; B-[2-Chloro-6-(trifluoromethyl)phenyl]boronic acid; 2-Chloro-6-trifluoromethylbenzeneboronic acid; Boronic acid, B-[2-chloro-6-(trifluoromethyl)phenyl]-; 851756-52-0; 2-Chloro-6-(trifluoromethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethyl)Phenylboronic Acid undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by NMR, HPLC, and elemental analysis, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.