Description

Lidocaine-D10 (N,n-Diethyl-D10) is a stable isotope-labeled analog of the widely used local anesthetic and antiarrhythmic agent, Lidocaine. This high-purity deuterated standard is essential for ensuring accuracy and reliability in quantitative mass spectrometry-based analyses. It is primarily utilized by pharmaceutical research and development laboratories, clinical research organizations, and analytical testing facilities for applications requiring precise internal standardization.

Application

• Used as an Internal Standard for the accurate quantification of Lidocaine and its metabolites in bioanalytical studies using LC-MS/MS and GC-MS.
• Critical for Pharmacokinetic and Metabolite Profiling research during drug development and clinical trials.
• Enables Therapeutic Drug Monitoring (TDM) in clinical settings to optimize patient dosage and ensure safety.
• Supports Forensic and Toxicology analyses for the definitive identification and measurement of Lidocaine in complex matrices.
• Facilitates Drug Impurity and Degradation Product studies by providing a reference marker in stability-indicating methods.
• Employed in Environmental and Food Safety Testing for trace analysis where isotopic dilution is required for highest precision.

Basic Information

Product Name	Lidocaine-D10 (N,n-Diethyl-D10)
CAS No.	851528-09-1
Molecular Formula	C14H12D10N2O
Molecular Weight	240.36 g/mol
Synonyms	2-(Diethylamino-d10)-N-(2,6-dimethylphenyl)acetamide; Lidocaine-d10; Lignocaine-d10; Xylocaine-d10; Deuterated Lidocaine; [Diethyl-d10]Lidocaine; N,N-Diethyl-d10-Lidocaine; Isotopic Labeled Lidocaine Internal Standard
EINECS	Contact for details

Quality Control

Our Lidocaine-D10 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by comprehensive analytical documentation, including detailed NMR and Mass Spectrometry data to confirm deuteration level and chemical identity. Certificates of Analysis (COA) specifying purity by HPLC, isotopic enrichment, and residual solvent content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuteration)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.