Description

2-Bromo-1-Fluoro-3-Iodobenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in the life sciences and specialty chemical industries who require reliable, high-quality intermediates for coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to create complex biaryl and heterobiaryl structures.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Diagnostic Agent Development: Utilized in research for radiolabeling precursors and fluorescent probes in medical imaging.

Basic Information

Product Name	2-Bromo-1-Fluoro-3-Iodobenzene
CAS No.	851368-08-6
Molecular Formula	C6H3BrFI
Molecular Weight	300.89 g/mol
Synonyms	1-Bromo-2-fluoro-3-iodobenzene; 2-Fluoro-6-bromo-1-iodobenzene; 3-Iodo-2-bromofluorobenzene; Benzene, 2-bromo-1-fluoro-3-iodo-; 2-Bromo-1-fluoro-3-iodo-benzene; 2-Bromo-6-fluoro-1-iodobenzene; 851368-08-6; 2-Br-1-F-3-I-C6H3
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Fluoro-3-Iodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.