Description

(S)-(-)-[(S)-2-Diphenylphosphinoferrocenyl][2-Diphenylphosphinophenyl]Methanol is a highly specialized chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in its ability to impart exceptional enantioselectivity and catalytic activity in transition metal-catalyzed reactions, enabling the production of high-value, optically pure intermediates. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing advanced active ingredients and novel materials.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C bond-forming reactions, including cross-coupling and allylic substitution.
• Key reagent in the development of stereoselective synthetic routes for complex natural products and active pharmaceutical ingredients (APIs).
• Use in academic and industrial R&D for exploring new catalytic transformations and optimizing existing processes.
• Potential application in the synthesis of chiral agrochemicals and specialty materials with specific optical properties.

Basic Information

Product Name	(S)-(-)-[(S)-2-Diphenylphosphinoferrocenyl][2-Diphenylphosphinophenyl]Methanol
CAS No.	851308-43-5
Molecular Formula	C41H33FeOP2
Molecular Weight	650.48 g/mol
Synonyms	(S,S)-JOSIPHOS SL-J009-1; (S)-(-)-[1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl]diphenylphosphine methanol adduct; (S,S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi(2-methoxyphenyl)phosphine; JOSIPHOS SL-J009-1 ligand; (S,S)-JOSIPHOS methanol adduct; Chiral ferrocenyl diphosphine ligand; (S,S)-Fc-PHOX type ligand
EINECS	Contact for details

Quality Control

Our production of (S)-(-)-[(S)-2-Diphenylphosphinoferrocenyl][2-Diphenylphosphinophenyl]Methanol adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.