Description

Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, N,n-Bis[(1S)-1-(4-Methoxyphenyl)Ethyl]-, (11Bs)- is a sophisticated chiral phosphine-amine ligand, a key building block in advanced asymmetric catalysis. Its value lies in enabling highly selective and efficient synthetic transformations, crucial for producing enantiomerically pure intermediates. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries seeking to optimize stereoselective reactions.

Application

• As a chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and agrochemicals.
• In academic and industrial R&D for developing novel catalytic systems and methodologies.
• As a key intermediate in the preparation of more complex, tailor-made phosphine ligands.
• For use in cross-coupling reactions where high stereocontrol is required.

Basic Information

Product Name	Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, N,n-Bis[(1S)-1-(4-Methoxyphenyl)Ethyl]-, (11Bs)-
CAS No.	850796-15-5
Molecular Formula	C36H34NO3P
Molecular Weight	559.63 g/mol
Synonyms	(11bS)-4-([(1S)-1-(4-Methoxyphenyl)ethyl]amino)-N-[(1S)-1-(4-methoxyphenyl)ethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (S)-DTBM-SEGPHOS Amine Derivative; Chiral BINOL-Derived Phosphoramidite Ligand Precursor; N,N-Bis[(S)-1-(4-Methoxyphenyl)ethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; Ligand L*; Asymmetric Catalyst Ligand 850796-15-5
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is moisture-sensitive and easily oxidized; allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.