Description

Potassium (4-Benzyloxy-2-Methylphenyl)Trifluoroborate is an organotrifluoroborate salt, a valuable and stable synthetic intermediate in modern cross-coupling chemistry. Its primary value lies in its enhanced stability and handling characteristics compared to boronic acids, offering superior shelf-life and reliability in demanding synthesis workflows. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for Suzuki-Miyaura coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring the introduction of specific aryl groups.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Serves as a versatile reagent for labeling and modifying biomolecules in diagnostic and research applications.
• Scale-up Process Chemistry: Its robust nature makes it suitable for optimization and scale-up from laboratory to pilot plant and manufacturing scales.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Product Name	Potassium (4-Benzyloxy-2-Methylphenyl)Trifluoroborate
CAS No.	850623-43-7
Molecular Formula	C14H13BF3KO
Molecular Weight	304.16 g/mol
Synonyms	Potassium (4-(Benzyloxy)-2-methylphenyl)trifluoroborate; Potassium 4-Benzyloxy-2-methylphenyltrifluoroborate; (4-Benzyloxy-2-methylphenyl)trifluoroborate Potassium Salt; 4-(Benzyloxy)-2-methylbenzenetrifluoroborate Potassium Salt; 2-Methyl-4-(phenylmethoxy)benzenetrifluoroborate Potassium Salt; Potassium Trifluoro(4-benzyloxy-2-methylphenyl)borate
EINECS	Contact for details

Quality Control

Our Potassium (4-Benzyloxy-2-Methylphenyl)Trifluoroborate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) when opening to prevent degradation. Keep container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹¹B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%
Potassium Content	12.0% - 13.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.