Description

2-Ethoxy-5-Trifluoromethylphenylboronic Acid is a high-value organoboron compound, specifically an arylboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing trifluoromethyl and aryl ether motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Employed in the development of organic electronic materials, including OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Cross-Coupling Reactions: Serves as a versatile reagent in Suzuki-Miyaura cross-coupling for the formation of carbon-carbon bonds in complex molecule assembly.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for new chemical entities.
• Ligand Synthesis: Can be utilized to create novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Ethoxy-5-Trifluoromethylphenylboronic Acid
CAS No.	850593-10-1
Molecular Formula	C9H10BF3O3
Molecular Weight	233.98 g/mol
Synonyms	(2-Ethoxy-5-(trifluoromethyl)phenyl)boronic acid; 2-Ethoxy-α,α,α-trifluoro-p-tolylboronic acid; Boronic acid, B-[2-ethoxy-5-(trifluoromethyl)phenyl]-; 5-Trifluoromethyl-2-ethoxyphenylboronic acid; 2-Ethoxy-5-trifluoromethylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-5-Trifluoromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.