Description

3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid is a high-value organoboron building block, specifically a substituted benzeneboronic acid derivative. This compound is essential for modern synthetic chemistry, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex, fluorinated target molecules. Its unique structure, featuring both fluoro and isobutoxy substituents, allows for precise tuning of electronic and steric properties in advanced material and ligand design.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for methodological development in palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Useful for constructing sophisticated bidentate or monodentate ligands for transition metal catalysis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals beyond life sciences.

Basic Information

Product Name	3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid
CAS No.	850589-57-0
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	[3-Fluoro-5-(2-methylpropoxy)phenyl]boronic acid; (3-Fluoro-5-isobutoxyphenyl)boronic acid; Boronic acid, B-[3-fluoro-5-[(2-methylpropyl)oxy]phenyl]-; 3-Fluoro-5-isobutoxybenzeneboronic acid; 5-Fluoro-3-isobutoxybenzeneboronic acid; CAS 850589-57-0; 850589-57-0
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Isobutoxy)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.