Description

3-Ethoxy-5-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precision and reliability in chemical synthesis are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the stability and reactivity of the boronic acid group.
• Material Science Research: Serves as a monomer or building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and sensors due to its selective reactivity.
• Catalyst Ligand Preparation: Can be utilized to synthesize novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-Ethoxy-5-Fluorobenzeneboronic Acid
CAS No.	850589-53-6
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(3-Ethoxy-5-fluorophenyl)boronic acid; 5-Fluoro-3-ethoxybenzeneboronic acid; 3-Ethoxy-5-fluorophenylboronic acid; Boronic acid, B-(3-ethoxy-5-fluorophenyl)-; 850589-53-6; 3-Fluoro-5-ethoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Ethoxy-5-Fluorobenzeneboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.