Description

5-Fluoro-2-Methoxycarbonylphenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require consistent, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides that incorporate fluorinated aromatic structures for enhanced efficacy and stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where fluorinated phenylboronic acids modify electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring specific fluorinated boronic acid derivatives.

Basic Information

Product Name	5-Fluoro-2-Methoxycarbonylphenylboronic Acid
CAS No.	850568-05-7
Molecular Formula	C9H10BFO4
Molecular Weight	212.00 g/mol
Synonyms	(5-Fluoro-2-(methoxycarbonyl)phenyl)boronic acid; 2-Carbomethoxy-5-fluorophenylboronic acid; Methyl 5-fluoro-2-boronobenzoate; 5-Fluoro-2-(methoxycarbonyl)benzeneboronic acid; 5-Fluoro-2-methoxycarbonylbenzeneboronic acid; Methyl 2-borono-5-fluorobenzoate; 850568-05-7; 5-Fluoro-2-methoxycarbonylphenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxycarbonylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.