Description

3-(Trifluoromethyl)-5-Methyl-Phenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient formation of carbon-carbon bonds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethylphenyl moiety, which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the unique properties of the fluorine atoms.
• Material Science: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex organic molecules via palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Can be used to create novel boronic acid-based ligands for catalysis or sensor applications.

Basic Information

Product Name	3-(Trifluoromethyl)-5-Methyl-Phenylboronic Acid
CAS No.	850411-13-1
Molecular Formula	C8H8BF3O2
Molecular Weight	203.96 g/mol
Synonyms	[3-(Trifluoromethyl)-5-methylphenyl]boronic acid; 5-Methyl-3-(trifluoromethyl)benzeneboronic acid; 3-Methyl-5-(trifluoromethyl)phenylboronic acid; (3-Trifluoromethyl-5-methylphenyl)boronic acid; Boronic acid, B-[3-(trifluoromethyl)-5-methylphenyl]-; 850411-13-1; 3-Trifluoromethyl-5-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-5-Methyl-Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is analyzed for identity, purity, and impurity profile. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.