Description

2-(3-Fluoro-Phenoxymethyl)-[1,3]Dioxolane is a specialized fluorinated dioxolane derivative, serving as a versatile building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both a fluorinated aromatic ether and a protected aldehyde functionality, enabling precise chemical modifications. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, particularly those targeting the central nervous system or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom and dioxolane group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for creating advanced electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Employed to introduce fluorinated aromatic ether groups into polymer chains, enhancing material properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: Functions as a protected aldehyde equivalent or a fluorinated synthon in multi-step synthetic routes for complex molecules in academic and industrial research.

Basic Information

Product Name	2-(3-Fluoro-Phenoxymethyl)-[1,3]Dioxolane
CAS No.	850348-80-0
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	2-[(3-Fluorophenoxy)methyl]-1,3-dioxolane; 1,3-Dioxolane, 2-[(3-fluorophenoxy)methyl]-; 3-Fluorophenyl 2,2-dimethyl-1,3-dioxolan-4-ylmethyl ether (related structure); Fluorophenoxymethyl dioxolane; FPMD (abbreviation); 850348-80-0; (3-Fluorophenoxymethyl)-1,3-dioxolane
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluoro-Phenoxymethyl)-[1,3]Dioxolane is produced and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.