Description

2-Pyrrolidinecarboxamide, 1-Formyl-n-Methyl-, (2S)- is a high-purity, chiral pyrrolidine derivative characterized by its specific stereochemistry at the 2-position. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Peptidomimetics: Serves as a constrained proline analog for designing novel peptide-like compounds with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the synthesis of chiral agrochemicals requiring specific stereochemistry for activity.

Basic Information

Product Name	2-Pyrrolidinecarboxamide, 1-Formyl-n-Methyl-, (2S)-
CAS No.	850246-88-7
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	(2S)-1-Formyl-N-methylpyrrolidine-2-carboxamide; (S)-1-Formyl-N-methylpyrrolidine-2-carboxamide; N-Methyl-1-formyl-L-prolinamide; L-Prolineamide, N-methyl-, 1-formyl-; 1-Formyl-N-methyl-L-prolinamide; (S)-1-Formyl-N-methyl-2-pyrrolidinecarboxamide; 850246-88-7; (2S)-1-Formyl-N-methyl-2-pyrrolidinecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxamide, 1-Formyl-n-Methyl-, (2S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.