Description

2-(6-Bromo-3-Pyridyl)-2-Methylpropanenitrile is a high-purity, versatile nitrile-substituted pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive bromo and cyano functional handle for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in the discovery and scale-up of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, insecticides, and fungicides, leveraging its halogen and nitrile functionalities.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic and electron-withdrawing cyano group.
• Custom Synthesis & Contract Manufacturing: A valuable scaffold for custom chemical synthesis services, supporting R&D projects requiring specific, high-value intermediates.

Basic Information

Product Name	2-(6-Bromo-3-Pyridyl)-2-Methylpropanenitrile
CAS No.	850197-45-4
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	2-(6-Bromo-3-pyridinyl)-2-methylpropanenitrile; 2-Methyl-2-(6-bromopyridin-3-yl)propanenitrile; 6-Bromo-3-(2-cyano-2-propyl)pyridine; α-(6-Bromo-3-pyridyl)isobutyronitrile; 850197-45-4; 2-(6-Bromopyridin-3-yl)-2-methylpropanenitrile
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-3-Pyridyl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.