Description

Pyrazinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- (9Ci) is a specialized Fmoc-protected amino acid derivative, a high-purity building block critical for advanced organic synthesis. Its primary value lies in enabling the precise construction of complex peptides and peptidomimetics, particularly those incorporating heterocyclic scaffolds. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical discovery, and advanced material science who require reliable, high-quality intermediates for solid-phase peptide synthesis (SPPS) and other sophisticated chemical processes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential assembly of custom peptides containing pyrazine-based unnatural amino acids.
• Pharmaceutical Research & Development: Used in the synthesis of novel drug candidates, particularly for creating peptidomimetics with enhanced metabolic stability and binding affinity.
• Agrochemical Discovery: Serves as a building block for developing bioactive peptides and peptide-like compounds with potential pesticidal or plant growth-regulating properties.
• Chemical Biology & Proteomics: Employed in the synthesis of labeled peptides, activity-based probes, and other tools for studying protein function and interactions.
• Material Science: Can be utilized to create functionalized polymers or surfaces with specific peptide sequences for biosensing or biocompatibility applications.

Basic Information

Product Name	Pyrazinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- (9Ci)
CAS No.	850013-92-2
Molecular Formula	C22H19N3O4
Molecular Weight	389.41 g/mol
Synonyms	Fmoc-3-(2-pyrazinyl)-L-alanine; Fmoc-L-3-(pyrazin-2-yl)alanine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyrazin-2-yl)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-pyrazinyl)-L-alanine; Fmoc-Pra(2-Pyz)-OH; Fmoc-3-(2-Pyrazinyl)-Ala-OH; Nα-Fmoc-3-(pyrazin-2-yl)-L-alanine
EINECS	Contact for details

Quality Control

Our Pyrazinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- (9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.