Description

6-Ethoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing the 5-(trifluoromethyl)pyridine moiety, which is prized for its metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, liquid crystals, and functional polymers through palladium-catalyzed coupling reactions.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	6-Ethoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	849934-85-6
Molecular Formula	C8H9BF3NO3
Molecular Weight	235.0 g/mol
Synonyms	5-(Trifluoromethyl)-6-ethoxypyridin-3-ylboronic acid; (6-Ethoxy-5-(trifluoromethyl)pyridin-3-yl)boronic acid; 3-Borono-6-ethoxy-5-(trifluoromethyl)pyridine; 849934-85-6; 6-Ethoxy-5-trifluoromethyl-3-pyridineboronic acid; Boronic acid, B-[6-ethoxy-5-(trifluoromethyl)-3-pyridinyl]-; AKOS005258310
EINECS	Contact for details

Quality Control

Every batch of 6-Ethoxy-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profile is supplied with each shipment to guarantee consistency and support your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.