Description

(R)-1-{(R)-2-[2-(Diphenylphosphino)Phenyl]Ferrocenyl}Ethyldi(2-Norbornyl)Phosphine is a highly specialized, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. This compound matters for its ability to impart exceptional enantioselectivity and catalytic activity in critical synthetic transformations, enabling the production of high-value, optically pure intermediates. It is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Critical for constructing stereogenic centers in active pharmaceutical ingredients (APIs), including chiral drugs for cardiovascular and central nervous system disorders.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and insecticides to enhance efficacy and reduce environmental impact.
• Cross-Coupling Reactions: Facilitates asymmetric C-C and C-X bond-forming reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, with high stereofidelity.
• Fine Chemical and Fragrance Production: Enables the synthesis of complex, chiral molecules used in flavors, fragrances, and advanced materials.
• Catalyst Screening & Development: A valuable tool in academic and industrial research for discovering new catalytic systems and optimizing reaction conditions.

Basic Information

Product Name	(R)-1-{(R)-2-[2-(Diphenylphosphino)Phenyl]Ferrocenyl}Ethyldi(2-Norbornyl)Phosphine
CAS No.	849925-29-7
Molecular Formula	C47H48FeP2
Molecular Weight	730.66 g/mol
Synonyms	(R,R)-Walphos SL-W008-1; (R)-1-[(R)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldi(2-norbornyl)phosphine; Walphos Ligand SL-W008-1; (R,R)-Di(2-norbornyl)phosphino Ferrocenyl Ethyl Phosphine; Chiral Ferrocenyl Phosphine Ligand; Josiphos-type Ligand; Asymmetric Hydrogenation Ligand; SL-W008-1
EINECS	Contact for details

Quality Control

Every batch of our (R)-1-{(R)-2-[2-(Diphenylphosphino)Phenyl]Ferrocenyl}Ethyldi(2-Norbornyl)Phosphine is manufactured and tested under strict quality management systems. We guarantee high chiral purity and chemical integrity through advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment to ensure compliance with your research and process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is moisture-sensitive and easily oxidized; prolonged exposure to air, light, or ambient humidity should be avoided to maintain stability and catalytic performance.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Moisture Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.