Description

(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]Ferrocenyl}Ethyldi(3,5-Xylyl)Phosphine CAS NO 849925-21-9 is a highly specialized, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. This compound is valued for its ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for the development and production of chiral active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids, amines, and alcohols.
• Catalyst component for asymmetric cross-coupling reactions, including Suzuki-Miyaura and Heck reactions, to construct chiral biaryl systems.
• Key reagent in asymmetric allylic substitution processes for creating chiral building blocks with quaternary stereocenters.
• Use in academic and industrial R&D for developing novel catalytic methodologies and optimizing existing synthetic routes.
• Production of chiral intermediates for pharmaceuticals such as β-blockers, antidepressants, and antiviral agents.
• Synthesis of chiral ligands and catalysts for agrochemicals, including herbicides and fungicides with specific stereochemistry.

Basic Information

Product Name	(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]Ferrocenyl}Ethyldi(3,5-Xylyl)Phosphine
CAS No.	849925-21-9
Molecular Formula	C51H48FeP2
Molecular Weight	778.69 g/mol
Synonyms	(S,S)-BPPFA; (S,S)-BPPFOH; (S,S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine; Josiphos SL-J009-1; (S)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; (S,S)-BPPF-A; Chiral Ferrocenyl Phosphine Ligand; SL-J009-1
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Every lot is characterized using advanced analytical techniques, including HPLC, NMR, and chiral analysis, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light will degrade its catalytic efficacy.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.