Description

(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldicyclohexylphosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in advanced asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the synthesis of complex, single-enantiomer molecules. This ligand is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for creating active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Asymmetric hydrogenation of prochiral olefins, ketones, and imines for pharmaceutical intermediate synthesis.
• Enantioselective cross-coupling reactions, including Suzuki-Miyaura and Negishi couplings.
• Catalyst component for asymmetric allylic substitution and alkylation reactions.
• Key ligand in the development of novel catalytic systems for academic and industrial research.
• Production of chiral compounds for use in agrochemicals and specialty materials.
• Process development and scale-up of enantiopure active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldicyclohexylphosphine
CAS No.	849925-19-5
Molecular Formula	C46H48FeP2
Molecular Weight	718.64 g/mol
Synonyms	(S,S)-JOSIPHOS SL-J009-1; (S)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine; Josiphos SL-J009-1; (S)-1-[(S)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldicyclohexylphosphine; (S,S)-JOSIPHOS ligand; (S,S)-J009-1; (S)-1-[(S)-2-(2-Diphenylphosphinophenyl)ferrocenyl]ethyldicyclohexylphosphine; Chiral ferrocenyl diphosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our (S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldicyclohexylphosphine is manufactured and tested under strict quality management systems to ensure exceptional purity and chiral integrity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC/NMR), and metal content. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.