Description

(R)-1-Dicyclohexylphosphino-2-[(S)- -(Dimethylamino)-2-(Dicyclohexylphosph is a highly specialized chiral phosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling the precise stereochemical control required for synthesizing complex, high-value pharmaceutical intermediates and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance ligands for cross-coupling and hydrogenation reactions.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure pharmaceutical actives.
• Catalyst component in cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig) for constructing complex molecular architectures.
• Critical reagent in the development and scale-up of novel synthetic routes for agrochemicals and specialty chemicals.
• Use in academic and industrial research for exploring new catalytic methodologies in organic synthesis.
• Production of chiral intermediates for active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• As a key component in catalyst screening kits for high-throughput experimentation (HTE) in process chemistry.

Basic Information

Product Name	(R)-1-Dicyclohexylphosphino-2-[(S)- -(Dimethylamino)-2-(Dicyclohexylphosph
CAS No.	849925-16-2
Molecular Formula	C26H49NP2
Molecular Weight	437.62 g/mol
Synonyms	(R)-1-Dicyclohexylphosphino-2-[(S)-2-(dimethylamino)cyclohexyl]ferrocene; Josiphos-type ligand derivative; Chiral Josiphos ligand; (R)-1-[(S)-2-(Dimethylamino)cyclohexyl]dicyclohexylphosphine; (R)-1-[(S)-2-(N,N-Dimethylamino)cyclohexyl]dicyclohexylphosphine; Chiral ferrocenylphosphine ligand; Asymmetric hydrogenation ligand SL-J009-1; (R)-1-[(S)-2-(Dimethylamino)cyclohexyl]dicyclohexylphosphane
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and performance reliability. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis to confirm chemical identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, it is recommended to store this product under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is advised. Handle and open containers in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.