Description

(As,As)-1,1'-Bis[4-(Dimethylamino)Benzyl]-(R,R)-2,2'-Bis(Dicyclohexylphosphino)-1,1'-binaphthyl is a sophisticated, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, a critical factor for producing optically pure pharmaceutical intermediates and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand for asymmetric hydrogenation reactions, particularly for the synthesis of enantiomerically pure amino acids and their derivatives.
• Catalyst component in asymmetric C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Key reagent in the development of novel catalytic systems for the production of active pharmaceutical ingredients (APIs).
• Use in academic and industrial R&D for exploring new asymmetric synthetic methodologies.
• Potential application in the synthesis of chiral ligands and auxiliaries for further catalytic cycles.

Basic Information

Product Name	(As,As)-1,1'-Bis[4-(Dimethylamino)Benzyl]-(R,R)-2,2'-Bis(Dicyclohexylphosphino)-1,1'-binaphthyl
CAS No.	849924-78-3
Molecular Formula	C66H84N2P2
Molecular Weight	975.33 g/mol
Synonyms	(R,R)-DACH-Phenyl-BINAP Derivative; (R,R)-DACH-Phenyl-Tol-BINAP; (R,R)-[4-(Dimethylamino)benzyl]-DACH-Phenyl-BINAP; (R,R)-2,2'-Bis(dicyclohexylphosphino)-1,1'-binaphthyl derivative; Chiral Josiphos-type ligand; Asymmetric bisphosphine ligand; (R,R)-DACH-Phenyl-ANP; (R,R)-DACH-Phenyl-MOP Analog
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and performance reliability. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis to confirm identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.