Description

(R)-1-{(S)-2-[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]Ferrocenyl}-Ethylbis(2- CAS NO 849924-49-8 is a highly specialized, chiral ferrocenylphosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, which are essential for the efficient and sustainable synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in their synthetic processes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure amino acids, amines, and alcohols.
• Catalyst component in asymmetric C-C bond-forming reactions, such as cross-couplings and allylic substitutions, for complex molecule construction.
• Key reagent in the synthesis of active pharmaceutical ingredients (APIs) where specific chirality is required for biological activity.
• Use in academic and industrial R&D for developing novel catalytic methodologies and exploring new chemical space.
• Potential applications in the synthesis of agrochemicals and flavors & fragrances that require chiral specificity.

Basic Information

Item	Detail
Product Name	(R)-1-{(S)-2-[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]Ferrocenyl}-Ethylbis(2- CAS NO 849924-49-8
CAS No.	849924-49-8
Molecular Formula	C41H45FeO2P
Molecular Weight	656.61 g/mol
Synonyms	(R)-1-[(S)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl]ethyldi(2-furyl)phosphine; Josiphos SL-J009-1; (R)-(S)-JOSIPHOS SL-J009-1; (R)-1-[(S)-2-(Di(2-furyl)phosphino)ferrocenyl]ethyldi(3,5-dimethyl-4-methoxyphenyl)phosphine; (R)-1-{(S)-2-[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]Ferrocenyl}Ethyldi-2-Furylphosphine; Ferrocenylphosphine ligand J009-1; Chiral Josiphos ligand derivative.
EINECS	Contact for details

Quality Control

Our high-value chiral ligands are produced and handled under strict quality control protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (argon or nitrogen) is recommended. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents (e.g., THF, DCM, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.