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(S)-1-{(R)-2-[Bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]-Ferrocenyl}Ethyldicy CAS NO 849923-15-5


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CAS No.:849923-15-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-1-{(R)-2-[Bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]-Ferrocenyl}Ethyldicy is a highly specialized, chiral ferrocenyl phosphine ligand, a critical component in asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in transition-metal-catalyzed reactions, enabling the production of single-enantiomer intermediates essential for advanced materials and pharmaceuticals. It is primarily needed by research and development chemists and process engineers in the fine chemical, pharmaceutical, and agrochemical industries for developing novel synthetic routes and scaling up production of chiral active ingredients.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
  • Catalyst component in asymmetric C-C bond-forming reactions (e.g., cross-coupling, allylic substitution).
  • Enantioselective synthesis of active pharmaceutical ingredients (APIs) and natural product analogs.
  • Development of custom catalyst systems for process chemistry and scale-up.
  • Research tool in academic and industrial R&D for exploring new asymmetric transformations.
  • Potential use in the synthesis of electronic materials and specialty chemicals requiring precise stereochemistry.

Basic Information

Product Name (S)-1-{(R)-2-[Bis[3,5-Bis(Trifluoromethyl)Phenyl]Phosphino]-Ferrocenyl}Ethyldicy
CAS No. 849923-15-5
Molecular Formula C34H21F12PFe
Molecular Weight 744.34 g/mol
Synonyms (S)-1-[(R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ferrocenyl]ethyldicyclohexylphosphine; Josiphos SL-J009-1; SL-J009-1; (S)-1-((R)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)phosphino)ferrocenyl)ethyldicyclohexylphosphine; Chiral Ferrocenyl Phosphine Ligand J009-1; (S)-1-[(R)-2-(Di(3,5-di(trifluoromethyl)phenyl)phosphino)ferrocenyl]ethyldicyclohexylphosphine
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Quality Control

Every batch of our chiral ligands is produced and tested under strict quality control protocols to ensure consistency and performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Purity ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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