Description

{4-[(2-Fluorophenyl)Methoxy]Phenyl}Methanamine CAS NO 849807-01-8 is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorinated phenyl ether and a primary amine group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of new active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for Schiff bases and other nitrogen-containing derivatives.
• Bioconjugation & Probe Development: The primary amine group is reactive for conjugation with biomarkers, fluorescent tags, or other bioactive molecules for diagnostic applications.

Basic Information

Product Name	{4-[(2-Fluorophenyl)Methoxy]Phenyl}Methanamine
CAS No.	849807-01-8
Molecular Formula	C14H14FNO
Molecular Weight	231.27 g/mol
Synonyms	1-{4-[(2-Fluorophenyl)methoxy]phenyl}methanamine; 4-[(2-Fluorobenzyl)oxy]benzylamine; (4-((2-Fluorobenzyl)oxy)phenyl)methanamine; 2-Fluoro-α-[[(4-aminomethyl)phenoxy]methyl]benzene; Benzenemethanamine, 4-[(2-fluorophenyl)methoxy]-; 849807-01-8; FC-AM-001 (example research code)
EINECS	Contact for details

Quality Control

Our {4-[(2-Fluorophenyl)Methoxy]Phenyl}Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.