Description

Cyclobutanecarboxylic Acid, 1-[[(4-Fluorophenyl)Amino]Carbonyl]- is a specialized organic compound featuring a cyclobutane core functionalized with a carboxylic acid group and a 4-fluorophenyl urea moiety. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors who require reliable, high-quality intermediates for creating novel active ingredients and exploring new molecular entities.

Application

This compound serves as a versatile intermediate in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorinated phenyl group for enhanced biological activity and stability.
• Chemical Biology & Proteomics: Employed as a specialty reagent or a precursor for activity-based probes to study enzyme function and protein interactions.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers with specific thermal or optical properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic chemistry research and method development.

Basic Information

Item	Details
Product Name	Cyclobutanecarboxylic Acid, 1-[[(4-Fluorophenyl)Amino]Carbonyl]-
CAS No.	849217-49-8
Molecular Formula	C12H12FNO3
Molecular Weight	237.23 g/mol
Synonyms	1-[(4-Fluorophenyl)carbamoyl]cyclobutanecarboxylic acid; N-(4-Fluorophenyl)cyclobutanecarboxamide-1-carboxylic acid; 4-Fluoro-N-(1-carboxycyclobutyl)aniline; Cyclobutanecarboxylic acid, 1-[(4-fluorophenyl)aminocarbonyl]-; 1-Carboxy-N-(4-fluorophenyl)cyclobutanecarboxamide
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 1-[[(4-Fluorophenyl)Amino]Carbonyl]- adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality management system is designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.