Description

3-Bromo-5-Fluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic motifs for enhanced activity.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs, semiconductors, and liquid crystals.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for diagnostic and biochemical research applications.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aromatic rings.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Bromo-5-Fluorophenylboronic Acid
CAS No.	849062-37-9
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(3-Bromo-5-fluorophenyl)boronic acid; 3-Bromo-5-fluorobenzeneboronic acid; B-(3-Bromo-5-fluorophenyl)boronic acid; 849062-37-9; 3-Bromo-5-fluoro phenylboronic acid; Boronic acid, B-(3-bromo-5-fluorophenyl)-; 3-Br-5-F-C6H3B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.