Description

2-Bromo-3,4,5,6-Tetrafluorophenylboronic Acid is a highly functionalized organoboron reagent, a key building block in modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex fluorinated aromatic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to create novel, potent, and selective fluorinated pesticides and herbicides with improved environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a key building block for fluorinated aromatic cores in electronic display and lighting materials, enhancing stability and performance.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and low surface energy.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl bonds under mild conditions.
• Chemical Research & Development: An invaluable tool for medicinal and process chemists exploring structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	2-Bromo-3,4,5,6-Tetrafluorophenylboronic Acid
CAS No.	849062-35-7
Molecular Formula	C6H2BBrF4O2
Molecular Weight	272.79 g/mol
Synonyms	(2-Bromo-3,4,5,6-tetrafluorophenyl)boronic acid; 2-Bromo-3,4,5,6-tetrafluorobenzeneboronic acid; B-(2-Bromo-3,4,5,6-tetrafluorophenyl)boronic acid; Boronic acid, B-(2-bromo-3,4,5,6-tetrafluorophenyl)-; 849062-35-7; 2-Br-3,4,5,6-F4PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,4,5,6-Tetrafluorophenylboronic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.