Description

2-Bromo-4,5-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the halogenated aromatic ring provides a versatile handle for further structural elaboration. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex, fluorinated biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel, fluorinated compounds for crop protection agents, leveraging the bioactivity-enhancing properties of fluorine atoms.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as fluorinated polymers or small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes, due to its reactive handles.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies.

Basic Information

Product Name	2-Bromo-4,5-Difluorophenylboronic Acid
CAS No.	849062-34-6
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(2-Bromo-4,5-difluorophenyl)boronic acid; 2-Bromo-4,5-difluorobenzeneboronic acid; B-(2-Bromo-4,5-difluorophenyl)boronic acid; 849062-34-6; Boronic acid, B-(2-bromo-4,5-difluorophenyl)-; 2-Bromo-4,5-difluorophenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.