Description

5-Butoxy-2-Fluorophenylboronic Acid is a specialized organoboron compound, specifically a fluorinated phenylboronic acid derivative. This chemical is a crucial building block in modern synthetic organic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a fluorinated biaryl scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and stability.
• Material Science Research: Serves as a monomer or building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that leverage boronic acid-diol interactions for detection applications.
• Catalyst & Ligand Preparation: Used to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences sector.

Basic Information

Product Name	5-Butoxy-2-Fluorophenylboronic Acid
CAS No.	849062-31-3
Molecular Formula	C₁₀H₁₄BFO₃
Molecular Weight	212.03 g/mol
Synonyms	(5-Butoxy-2-fluorophenyl)boronic acid; 2-Fluoro-5-butoxyphenylboronic acid; 5-Butoxy-2-fluorobenzeneboronic acid; Boronic acid, B-(5-butoxy-2-fluorophenyl)-; 849062-31-3; 5-n-Butoxy-2-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Butoxy-2-Fluorophenylboronic Acid is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (HPLC/NMR), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.