Description

trans-2-(3-Fluorophenyl)Vinylboronic Acid is a high-value organoboron building block characterized by its trans-configured vinyl group and fluorinated aromatic ring. This compound is essential for modern synthetic chemistry, enabling efficient cross-coupling reactions to create complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated biphenyl and stilbene derivatives with potential biological activity.
• Agrochemical Research: Used to construct fluorinated scaffolds in the discovery of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or building block for creating fluorinated conjugated polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of fluorophore-labeled probes and bioconjugates for imaging and diagnostic applications.
• Catalyst Ligand Synthesis: Useful for preparing novel bidentate or monodentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluorovinylphenyl moiety.

Basic Information

Product Name	trans-2-(3-Fluorophenyl)Vinylboronic Acid
CAS No.	849062-22-2
Molecular Formula	C8H8BFO2
Molecular Weight	165.96 g/mol
Synonyms	(E)-2-(3-Fluorophenyl)ethenylboronic Acid; trans-2-(3-Fluorostyryl)boronic Acid; (E)-3-Fluorostyrylboronic Acid; B-[(1E)-2-(3-Fluorophenyl)ethenyl]boronic Acid; 3-Fluoro-trans-styrylboronic Acid; (E)-2-(3-Fluorophenyl)vinylboronic Acid; trans-3-Fluorostyrylboronic Acid
EINECS	Contact for details

Quality Control

Our trans-2-(3-Fluorophenyl)Vinylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and 1H/11B/19F NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.